Part 1: When Flint Lockwood’s latest contraption accidentally destroys the town square and rockets up into the clouds, he thinks his inventing career is over. Then, something amazing happens as delicious cheeseburgers start raining from the sky. His machine actually works! But when the machine starts to run amok, it's up to Flint, with the help of weather girl Sam Sparks to find some way to shut down the machine and save the day.

Part 2: Inventor Flint Lockwood thought he saved the world when he destroyed his most infamous invention - a machine that turned water into food causing cheeseburger rain and spaghetti tornadoes. But Flint soon learns that his invention survived and is now combining food and animals to create "foodimals!" Flint and his friends embark on a dangerously delicious mission to battle hungry tacodiles, shrimpanzees, hippotatomuses, cheespiders and other foodimals to save the world – again!